t is well established that Paxil carries a risk of suicide in children and teens. Nonetheless, GlaxoSmithKline has been conducting a study of the antidepressant using children as young as seven. The drug carries a “black box” stating that it is twice as likely to generate lethal thoughts as a placebo. BNET reports:“ The primary aim of the study is not to find out why Paxil makes some children kill themselves. Rather, it’s yet another efficacy study, which the drug doesn’t need because it was approved years ago … If the results suggest a lower suicide risk, expect GSK to play them up. If they’re bad, expect the company to dismiss them in favor of the primary endpoint results.” The link between suicide and antidepressants like Paxil is so strong that they are required to carry black box warning labels detailing the risk. In young adults, particularly, the link is glaring and GlaxoSmithKline (GSK) even sent a warning letter to physicians in 2006 alerting them that Paxil may increase the risk of suicide attempts in young adults. Despite this, or more likely because of it, the company is now carrying out a study in Japan to test the efficacy of Paxil versus a placebo in children with depression. They are actively recruiting children between the ages of 7 and 17 years, who may be among the most vulnerable to Paxil’s suicidal side effects.Why would GlaxoSmithKline test Paxil on kids? It’s clearly not to find out whether it’s effective the drug is already approved, so this is a moot point. Instead, they are likely hoping that, come September 2010 when the study is supposed to be completed, they can somehow present their results to show that Paxil is not so bad after all. ![061129_paxil_hmed_930a.hmedium[1]](http://5magazine.files.wordpress.com/2010/06/061129_paxil_hmed_930a-hmedium1.jpg)
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